Inhibitory Effect of Garlic and Vitamin C on Candida Albicans

Highlight: 1. Garlic and Vitamin C effect on Candida Albicans. 2. has the ability to inhibit C. albicans in PBS media but it did not have significant MIC due presence of glucose if combined with garlic petroleum extract. Abstract: can downregulate ECE1, a gene that regulates production candidalysin as virulence factor for albicans. Allicin antifungal properties because allicin penetrate cell membranes damage organelles such vacuoles mitochondria, causing irreversible structural functional leads death. is processed into extracts also abilities. Purely squeezed extract had 50%, while ethanol 40%. This difference thought be differences use concentrations used solvents. media, there an active metabolism oxygen, low free iron concentration, mitochondrial inhibition ongoing, early stationary growth phase. However, combination ether vitamin show which could increase C.albicans.